embitter
verb- embitter somebody
to make somebody feel angry or disappointed about something over a long period of time 使怨愤；使沮丧；使苦恼 Years of caring for her ageing parents had embittered her. 多年来对年迈父母的照顾使她痛苦不堪。 They were becoming deeply embittered by the government’s lack of concern. 由于政府缺乏关心，他们变得非常痛苦。 What had embittered them most of all was their exclusion from the judicial process. 最让他们痛苦的是他们被排除在司法程序之外。