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BNC: 26419 COCA: 25642

refractory

adjective
/rɪˈfræktəri/
/rɪˈfræktəri/
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  1. (formal) (of a person人) difficult to control; behaving badly难以驾驭的；行为乖戾的
  2. (medical医学) (of a disease or medical condition疾病或身体状况) difficult to treat or cure难以诊治的；难以治愈的
    3. Word Originearly 17th cent.: alteration of obsolete refractary, from Latin refractarius ‘stubborn’ (see also refract).

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