a disease spread by sexual contact 梅毒 - (also smallpox)
(in the past 旧时 a serious disease that caused a high temperature, left permanent marks on the skin and often caused death 痘： 一种引起高温的严重疾病，在皮肤上留下永久性痕迹，经常导致死亡
Word Originlate Middle English: alteration of pocks, plural of pock ‘pockmark’.