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first of all
  1.  
     before doing anything else; at the beginning第一；首先
    • First of all, let me ask you something.首先，让我问你一件事。
    Language Bank processprocessDescribing a process描述过程
      • This diagram illustrates the process of paper-making./This diagram shows how paper is made.这个图说明了造纸的过程。
      • First/First of all, logs are delivered to a paper mill, where the bark is removed and the wood is cut into small chips.首先，原木被运送到造纸厂，在那里去掉树皮，然后被切成木片。
      • Next/Second, the wood chips are pulped, either using chemicals or in a pulping machine.接下来，用化学品或磨浆机把木片化成浆。
      • Pulping breaks down the internal structure of the wood and enables/allows the natural oils to be removed.制浆过程使木材的内部结构分解，从而去除木材里的天然油。
      • Once/After the wood has been pulped, the pulp is bleached in order to remove impurities. /…is bleached so that impurities can be removed.木材制成浆后，将其漂白以去除杂质。
      • The next stage is to feed the pulp into the paper machine, where it is mixed with water and then poured onto a wire conveyor belt.下一步便是将纸浆送入制纸机，与水混合后再倒入金属传送带。
      • As the pulp travels along the conveyor belt, the water drains away. This causes the solid material to sink to the bottom, forming a layer of paper.当纸浆沿传送带传送时，水分蒸发，使得固体物质沉到底部，形成一层纸。
      • At this point the new paper is still wet, so it is passed between large heated rollers, which press out the remaining water and simultaneously dry the paper/…dry the paper at the same time.这时，新出的纸仍然是湿的，故让其经过几个巨大的热滚筒，挤压脱水并同时烘干。
      • The final stage is to wind the paper onto large rolls./Finally, the paper is wound onto large rolls.最后一步是将纸卷在巨大的卷轴上。
  2.  
     as the most important thing最重要；首先
    • The content of any article needs, first of all, to be relevant to the reader.任何文章的内容都首先要与读者有关。
Which Word? firstly / first of all / at firstfirstly / first of all / at first
  • Firstly and first (of all) are used to introduce a series of facts, reasons, opinions, etc:firstly 和 first (of all) 均用以引出一系列事实、理由、意见等：
    • The brochure is divided into two sections, dealing firstly with basic courses and secondly with advanced ones.小册子分为两部分：第一部分涉及基础课程，第二部分涉及高级课程。
    Firstly is more common in British English than in North American English.
  • At first is used to talk about the situation at the beginning of a period of time, especially when you are comparing it with a different situation at a later period:
    • Maggie had seen him nearly every day at first. Now she saw him much less.起初玛吉几乎每天都见到他，现在见到他的次数少得多了。
See also first
first of all
Words and expressions when listing things: secondly, firstly, lastly...
Before a time or event: before, first, early...

See also: first/best/most etc of all

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